NEW YORK --?New England Patriots?quarterback Tom Bradys latest attempt to avoid serving a four-game Deflategate suspension to start the new season was flatly rejected Wednesday by an appeals court.The 2nd U.S. Circuit Court of Appeals in Manhattan issued a one-sentence rejection of requests by the National Football League Players Association and Brady to reconsider an April decision that found that NFL commissioner Roger Goodell acted?within his powers by suspending the star quarterback for his role in a scheme to doctor footballs used in a January 2015 playoff game.We are disappointed with the decision denying a rehearing, as there were clear violations of our collective bargaining agreement by the NFL and Commissioner Roger Goodell, the NFLPA said in a statement issued Wednesday. Despite todays result, the track record of this League office when it comes to matters of player discipline is bad for our business and bad for our game. We have a broken system that must be fixed.We will review all of our options carefully on behalf of Tom Brady and all NFL players.The NFL declined comment.The courts action leaves intact the 2-1 ruling by a three-judge panel that affirmed wide-ranging powers given to the commissioner by the NFLs collective bargaining agreement. It is a setback for organized labor groups arguing for due process in employee discipline.The players association and Brady had requested that the three-judge panel reconsider the case or that all the 2nd Circuit judges hear arguments and decide anew.Bradys remaining hope is to appeal to the U.S. Supreme Court.Sources close to Bradys legal team told ESPNs Mike Reiss on Wednesday that the denied appeal was the expected result and that no decision has been made concerning the next step.We wish the result were otherwise, but respect and understand the decision and know that it is extremely rare for the Second Circuit to grant en banc review,?Anthony Barkow, a lawyer who submitted a brief on behalf of longtime arbitrator Kenneth R. Feinberg, told The Associated Press.An en banc review would be a new hearing in front of the complete circuit.The Patriots open the season Sept. 11 at Arizona. If Brady remains suspended, backup quarterback Jimmy Garoppolo?is expected to take his place against the?Cardinals,?Miami Dolphins, Houston Texans and Buffalo Bills.Despite the courts denial, the Patriots remain the odds-on favorite?-- at 6-1, with a regular-season win total of 10.5 --?to win Super Bowl LI, according to the Westgate Las Vegas SuperBook.Brady, who signed a two-year contract extension during the offseason that dropped his 2016 salary from $9 million to $1 million to save himself almost $2 million in lost salary during the suspension, would then make his regular-season debut in Week 5 against the Cleveland Browns. His renegotiated deal?deferred $8 million of his 2016 salary to later in the contract.What began as an accusation of cheating in the 2015 AFC Championship Game has grown into a multimillion-dollar legal battle over three NFL seasons involving not just an MVP quarterback but also some of the elite lawyers and scientists in the country.As it developed, it evolved from a dispute about the air pressure in footballs into a referendum on the powers of a sports commissioner and the right of all unionized employees to due process in a disciplinary hearing.Joining the case along the way were longtime league adversary Jeffrey Kessler and former U.S. Solicitor General Ted Olson, who was involved in the Bush v. Gore lawsuit that settled the 2000 presidential election and the case that overturned Californias ban on same-sex marriage in 2010. The AFL-CIO and scholars from some of the top legal and scientific institutions in the country also piped in with briefs.At stake for the Patriots was not only the availability of their quarterback for one-quarter of the season but also their legacy as an NFL dynasty. Goodell had already penalized the Patriots for cheating -- in an illegal-videotaping scheme in 2007 that came to be known as Spygate -- and they saw the suspension as an attack on their legitimacy of the four Super Bowl championships earned under Brady and coach Bill Belichick.The suspicions boiled over on Jan. 18, 2015, when the league tested the footballs provided by the home team for the AFC title game against the Indianapolis Colts and found them to be underinflated.After three months of analysis, league investigator Ted Wells found that the Patriots intentionally used underinflated footballs in the game and that Brady was at least generally aware of the scheme. The NFL suspended the four-time Super Bowl champion quarterback four games and docked the team $1 million and two draft picks.Brady appealed, first within the league, and Goodell affirmed the decision. The quarterback appealed to federal court, and U.S. District Judge Richard Berman overturned the suspension in September 2015. The league appealed to the 2nd Circuit, and the three-judge panel reinstated the original penalty.An en banc review was unlikely, but Bradys last chance is an even more unlikely hearing at the Supreme Court.Thats always an option to litigants, Olson said after joining the case in May. It is not something we have resolved ourselves to doing.New England fans rallied behind their quarterback, putting Free Brady on T-shirts, reciting the ideal gas law from memory and giving a heros welcome to the quarterback when he took the field for the 2015 regular-season opener.ESPN Staff Writer Mike Reiss and The Associated Press contributed to this report. 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Isner, ranked No. 14, won his eighth career singles title and took the title in New Zealand for the second time after his victory in 2010. The match was similar to Isners quarterfinal victory over fifth-seeded Philipp Kohlschreiber which went to three sets, all tiebreaks and contained no breaks of serve. Montrezl Harrell Jersey . President of baseball operations Larry Beinfest was fired Friday after 12 years with the Marlins. The move came as the team neared the end of its third consecutive last-place season in the NL East. MINNEAPOLIS -- For most kickers, a game-tying, 58-yard field goal as time expires would qualify as the highlight of their careers.For Matt Prater, it just barely made the top five on his list.Praters big leg got the Detroit Lions to overtime against the Minnesota Vikings and Matthew Staffords big arm took over from there in a 22-16 victory on Sunday.Prater has the NFL record of 64 yards and three kicks of 59 yards on his resume, so when he trotted on to the field at indoor U.S. Bank Stadium with the game on the line, it was nothing new for him.Im confident, Prater said. More than likely Im not worried about missing it short. ... I expect to make every kick. I dont overanalyze it or think too much. I just kick it and hope it goes straight.It usually does. Prater is 23 for 23 on game-tying or go-ahead field goal tries in the fourth quarter or overtime, according to ESPN. So when Stafford took the ball down 16-13 with 23 seconds left on the clock, he knew all Prater needed was a chance.Matt Prater will say get to midfield and he will have a chance, Stafford said. He has got a big leg.Once it got to overtime, Stafford hit Golden Tate for a 28-yard touchdown to give the Lions (5-4) their fourth win in five games. Stafford completed 23 of 36 passes for 219 yards, two touchdowns and one interception and Tate had 11 catches for 79 yards.Sam Bradford completed 31 of 40 passes for 273 yards and a touchdown for the Vikings, who have lost three in a row coming out of the bye after a 5-0 start.But the vaunted Vikings defense couldnt come up with one more stop.Its hard to feel good after a loss, but today we looked like we have in the past, Vikings coach Mike Zimmer said.Obviously we didnt get it done and theres no guarantees, but Id rather go into a fight with these guys the way they were today than the last couple of weeks.Here are the top takeaways from the game:WALSHS BREAKING POINTJuxtaposed against Praters dependability in big moments is Vikings kicker Blair Walshs erratic play. He missed his third extra point try of the season, more than any other kicker in the league. He also had a kick that was blocked. Throughout his career, Walsh has impresseed with his graciousness in fielding questions after missing big kicks.dddddddddddd. But on Sunday, he snapped.It didnt go in, right? he said. You guys are going to ask me this question a million times: `Did it feel good? Did I make it? No. Do I have to? Yes. Do I want to? Yes. So, just, if youve got something else, please. Seriously.STAFFORDS COOLThe comeback was Staffords fifth this season when trailing in the fourth quarter, the most in the NFL. The Lions five victories have been by a total of 17 points. Their four losses have come by a combined 18 points.You do not always want to be in those situations, but we have been the majority of the time this year and these guys just believe in each other, Stafford said. I believe in those guys.ZIMMERS REGRETZimmer deployed a prevent defense in hopes of avoiding getting beaten deep by Stafford. When the QB was able to complete two passes to get them into Praters range, Zimmer said he should have tried to apply more pressure.If I had to do it all over again, I would probably rush four and try and get it that way, Zimmer said. He scrambled around and made a play. Thats how it goes.SHARP SHURMURUnlike the past two games, the blame for losing didnt fall squarely on Minnesotas offense.Actually, the Vikings posted their third-highest yardage total of the season during an efficient, rhythmic performance behind sharp play calling by offensive coordinator Pat Shurmur in his first game in the role. He replaced Norv Turner, who abruptly resigned on Wednesday.They used a faster pace between snaps and favored quicker, high-percentage throws, effectively minimizing the pressure on Bradford, who was sacked only twice after taking a total of 11 sacks the previous two weeks.Still, the Vikings werent perfect. They had to punt after starting a drive at the 18-yard line following an interception in the second quarter. Then in the fourth quarter, Matt Asiata was stopped for no gain on fourth-and-1 at the 5.---For more NFL coverage: http://www.pro32.ap.org and http://www.twitter.com/AP-NFL ' ' '